hCG May Offer Protection Against Breast Cancer


“The concept that hCG protects against breast cancer is based on epidemiology, animal studies, culture experiments, and clinical research that reported reduced breast cancer risk in nonobese women who took hCG as a part of a weight-loss regimen.”

Abstract: Recent studies found that human and animal breast tissues and human breast cell lines contain low levels of receptors that bind hCG and its structural and functional homologue, LH. Those gonadotropins exert numerous anticancer effects in breast cancer models and cells, which might explain decreased breast cancer incidence in women who complete full-term pregnancies at a young age. The new findings also imply that premature chronic elevations of LH levels might contribute to decreased breast cancer incidence in women with early menopause, and elevated LH levels might contribute to a better prognosis after ovariectomy. Those findings predict that breast cancer risk might be reduced by early hCG treatment of women who plan to delay their first pregnancies; prophylactic hCG treatment might help women with family histories of breast cancer or oncogene mutations that predict breast cancer; and better prognoses might result when hCG is administered to breast cancer tissue. (Obstet Gynecol 2000;96:783– 6. © 2000 by The American College of Obstetricians and Gynecologists.)

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