Homocysteine (part of our Initial Anti-Aging Screening Test Panel)  is a major risk factor heart disease and stroke.  It’s also a risk factor for Alzheimer’s disease, cancer, osteoporosis, neuropsychiatric disorders, etc.  Homocysteine is toxic to the blood vessel walls in the heart and the brain, causing endothelial dysfunction, oxidative stress/free radicals, neuronal DNA damage, cerebral microangiopathy, apoptosis of neural cells and mitochondrial membrane damage.

Factors that may cause homocysteine level to increase: toxins, medications, age, smoking,  hypothyroidism, renal failure or hereditary. The ideal level of homocysteine is 7-10 umol/L (6-8 is the optimal level).  

If too high:

  • Folic acid 800 mcg
  • Vit B6 40 mg
  • Vit B12 200 mcg daily
  • Betaine HCL (Trimethylglycine) 500 – 1000 mg
  • MTHF (active form of folic acid)
  • Garlic 1000 mg
  • SAMe 400 mg
  • Beets, broccoli

Too low: too low a level is usually associated with over methylation.

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