Many, if not all, vitamins and micronutrients do not work alone in our body. They work in synergistic, antagonistic or interdependent manners. While the synergistic and antagonistic actions are well known, the interdependent manner is much less known. Here are some examples of this “interdependency”
- B vitamins cannot do their job without enough omega-3s, and vice versa: https://foodforthebrain.org/campaigns/alzheimers-prevention/omega-3-and-b-vitamins/#:~:text=associated%20with%20Alzheimer’s.-,B%20vitamins%20found%20not%20to%20work,omega%2D3%20and%20vice%20versa&text=Also%2C%20at%20the%20end%20of,benefit%20from%20the%20B%20vitamins.
- Young, L.M.; Gauci, S.; Arnoldy, L.; Martin, L.; Perry, N.; White, D.J.; Meyer, D.; Lassemillante, A.-C.; Ogden, E.; Silber, B.; Scholey, A.; Pipingas, A. Investigating the Effects of a Multinutrient Supplement on Cognition, Mood and Biochemical Markers in Middle-Aged Adults with ‘Optimal’ and ‘Sub-Optimal’ Diets: A Randomized Double Blind Placebo Controlled Trial. Nutrients 2022, 14, 5079. https://doi.org/10.3390/nu14235079
- Liao S, Omage SO, Börmel L, Kluge S, Schubert M, Wallert M, Lorkowski S. Vitamin E and Metabolic Health: Relevance of Interactions with Other Micronutrients. Antioxidants (Basel). 2022 Sep 9;11(9):1785. doi: 10.3390/antiox11091785. PMID: 36139859; PMCID: PMC9495493.
- Vit D and K on bone health: https://www.foodandnutritionjournal.org/pdf/vol10no3/Nutrition_Vol10_No3_840-857.pdf
- Non drug intervention on glaucoma: Fahmideh F, Marchesi N, Barbieri A, Govoni S, Pascale A. Non-drug interventions in glaucoma: Putative roles for lifestyle, diet and nutritional supplements. Surv Ophthalmol. 2022 May-Jun;67(3):675-696. doi: 10.1016/j.survophthal.2021.09.002. Epub 2021 Sep 23. PMID: 34563531.