大剂量静脉VC及过氧化氢治疗基孔肯雅病毒感染(Chikungunya)

基孔肯雅热(Chikungunya)是一种以严重关节痛为特征的病毒性疾病,可能持续数月至数年。没有有效的治疗方法。 2014年7月至2014年10月,我们单次输注25-50克抗坏血酸(VC)和过氧化氢(H2O2)(3 cc的3%溶液)治疗56例中度至重度持续性疼痛患者。使用Verbal Numeric Rating Scale-11 询问患者治疗前后的疼痛情况。治疗前后的平均疼痛评分分别为8和2(60%)(p <0.001); 5例患者(9%)的疼痛评分为0。在中度至重度疼痛的基孔肯雅病毒患者中,大剂量静脉VC及过氧化氢的使用可导致统计学上显着的疼痛减轻。

Marcial-Vega VIdxian Gonzalez-Terron GLevy TE. 2014,PMID: [26035980]

Chikungunya is a viral illness characterized by severe joint pains, which may persist for months to years. There is no effective treatment for this disease. We treated 56 patients with moderate to severe persistent pains with a single infusion of ascorbic acid ranging from 25-50 grams and hydrogen peroxide (3 cc of a 3% solution) from July to October 2014. Patients were asked about their pain using the Verbal Numerical Rating Scale-11 immediately before and after treatment. The mean Pain Score before and after treatment was 8 and 2 respectively (60%) (p < 0.001); and 5 patients (9%) had a Pain Score of 0. The use of intravenous ascorbic acid and  hydrogen peroxide resulted in a statistically significant reduction of pain in patients with moderate to severe pain from the Chikungunya virus immediately after treatment.

Marcial-Vega VIdxian Gonzalez-Terron GLevy TE. 2014,PMID: [26035980]